Compound profile · Recovery research

5-Amino-1MQ

A small-molecule NNMT inhibitor studied in metabolic and adipose research.

Tissue research METS verified
StatusResearch use only
BPC-157
BPC-157
Dhs. 300.00
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01

Releasing the brake.

5-Amino-1MQ is not a peptide but a small-molecule inhibitor of NNMT (nicotinamide N-methyltransferase) - an enzyme over-active in some adipose and metabolic tissue. Inhibiting it is studied as a way to raise cellular NAD+ and influence fat-cell metabolism.

01
NNMT inhibition
Blocks an enzyme that consumes NAD+ precursors in fat tissue.
02
Metabolic models
Animal studies link inhibition to reduced fat mass and improved metabolism.
03
Oral interest
Studied in oral research formats rather than injection.
Class
Small molecule · NNMT inhibitor
NNMT inhibitor · small molecule
Calculate your reconstitution dosage →
03

At a glance

NNMT
Amino acids
NAD+
Min half-life (rat)
Oral
CAS
04

A metabolic switch, in early study.

NNMT sits at a junction of NAD+ metabolism and methylation. In tissues where it is over-expressed, it may drain the precursors cells use to make NAD+ - a coenzyme central to energy metabolism.

5-Amino-1MQ research is early - promising animal metabolic data on a specific enzymatic target. It sits in a different bucket from the peptides here: a small molecule, not a peptide.

05

Reading the evidence honestly

Tier 01
Strongest support
  • NNMT enzyme inhibition (biochemically characterised)
  • Reduced adiposity in rodent metabolic models
  • NAD+-pathway involvement
Tier 02
Moderate / preclinical
  • Improved metabolic markers in animals
  • Muscle / energy-metabolism signals
  • Mechanistic plausibility for body composition
Tier 03
Emerging / unverified
  • Human efficacy and dosing
  • Long-term safety
  • Weight / physique claims in humans
06

How it works

01
NNMT inhibition

Blocks nicotinamide N-methyltransferase activity.

Characterised
02
NAD+ pathway

May preserve NAD+ precursors in metabolic tissue.

Mechanistic
03
Adipose effect

Linked to reduced fat mass in rodent studies.

Animal models
04
Energy metabolism

Studied for effects on cellular energetics.

Early
07

How it moves through the system

AdministrationPeakHalf-lifeCleared
Peak 50% Cleared
~1 h
Onset to peak
hours
Half-life
~1 day
Largely cleared
Curve shape is illustrative; figures reflect pharmacokinetics reported in research — rapid local metabolism, figures from animal IV/IM data.
08

Used in the lab, not the clinic

Reference figures describe how this compound is handled and dosed in research. These are not instructions for human use.

Format & handling
Research formatOral capsule
ReconstitutionSmall molecule
Cold-chainRoom-temp stable
In the literature
Doses in literaturemg-scale (animal)
StorageCool, dry
Stability (reconstituted)Preclinical
09

Reconstitution calculator

How much diluent to mix into the vial, and the concentration that results. The suggested volume reaches a clean working stock; the calculator does the arithmetic from figures you enter. These describe solution preparation for research handling — not instructions for use in humans or animals.

Suggested reconstitution Reconstitute the 10 mg vial with 2 mL bacteriostatic water → 5.0 mg/mL (5000 mcg/mL)
Concentration—
Volume / aliquot—
U-100 units—
Aliquots / vial—
Concentration = compound ÷ diluent. Volume per aliquot = target ÷ concentration. U-100 units are a volume readout (1 mL = 100 units). Figures are for research solution preparation only — not instructions for use in humans or animals.
010

Signs of a quality compound

Lyophilised cake or powder
A fine, fluffy white cake — not oily, clumped or discoloured.
Clear reconstitution
Dissolves to a clear, colourless solution with no visible particles or cloudiness.
Batch-specific COA
Independent HPLC purity and mass-spec identity for the exact lot — not a recycled generic PDF.
Intact seal & vacuum
Sealed flip-top vial under vacuum; correct fill; legible batch and storage marking.
Walk away if…
No COA, oily residue, off-colour, partial vacuum, or purity claims with no independent test behind them.
Suspiciously cheap
Pricing far below the market for a well-tested compound usually means skipped testing or underfilled vials.
Regulatory & status
Early, mechanistic, unproven in humans.

5-Amino-1MQ is an investigational research chemical. The evidence to date is preclinical.

Status
Research chemical
2026 shift
Preclinical / animal
Approval
Not FDA-approved
Anti-doping
Small molecule, not a peptide
Research handling
Important notices
  • For research purposes only
  • Not for human consumption
  • Not FDA approved
  • Consult a qualified professional
Important

For research use only. Not for human consumption. Apex Academy is an educational reference describing findings reported in published and preclinical literature. Nothing here is medical advice, a protocol, or a recommendation to administer any compound to humans or animals. Many compounds described are investigational and are not approved by the FDA or other regulators for the prevention, treatment, or cure of any condition. Their long-term safety and pharmacokinetics remain incompletely characterized. Dose ranges, where shown, describe quantities used in cited research models - not instructions for use. Consult a qualified, licensed professional before making any health decision.