Compound profile · Recovery research

KPV

A small peptide studied for calming inflammation, especially in the gut.

Tissue research METS verified
StatusResearch use only
BPC-157
BPC-157
Dhs. 300.00
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01

Three letters, one job.

KPV is the tail end of the α-MSH hormone, distilled to a three-amino-acid peptide that keeps the anti-inflammatory action without the pigmentation effects. Most interest sits in the gut.

01
Anti-inflammatory core
Retains α-MSH's calming action on inflammation.
02
Gut focus
Studied in colitis and inflammatory-bowel models.
03
Flexible routes
Researched orally and topically as well as injected.
Primary structure
Lys-Pro-Val
Lys-Pro-Val · 3 amino acids
Calculate your reconstitution dosage →
03

At a glance

3
Amino acids
NF-κB
Key pathway
Gut
Main focus
04

Where the research focuses.

01
Gut inflammation

Studied in colitis / IBD models for reducing intestinal inflammation.

02
Skin inflammation

Researched topically for inflammatory skin conditions.

03
General anti-inflammatory

Down-regulates inflammatory signalling broadly.

04
Recovery support

Paired with repair peptides for an anti-inflammatory angle.

05

Calming, without the colour.

KPV keeps α-MSH's anti-inflammatory signalling - dialling down NF-κB and inflammatory cytokines - but drops the pigmentation effect of the parent hormone.

Its stability and oral activity make it a frequent subject in gut-inflammation research.

06

Strength of the evidence.

Tier 01
Strongest support
  • Anti-inflammatory mechanism (NF-κB) characterised
  • α-MSH lineage well understood
Tier 02
Moderate support
  • Colitis / IBD model data
  • Topical anti-inflammatory studies
Tier 03
Emerging / unverified
  • Human efficacy and dosing
  • Systemic recovery claims
07

How it works

01
NF-κB

Suppresses a master inflammatory signalling pathway.

Characterised
02
Cytokines

Lowers pro-inflammatory cytokine output.

Preclinical
03
Gut barrier

Supports intestinal lining integrity in models.

Animal models
04
Oral activity

Retains activity by oral and topical routes.

Research
08

How it moves through the system

AdministrationPeakHalf-lifeCleared
Peak 50% Cleared
minutes
Onset to peak
short
Half-life
hours
Largely cleared
Curve shape is illustrative; figures reflect pharmacokinetics reported in research - rapid local metabolism, figures from animal IV/IM data.
09

Reconstitution calculator

How much diluent to mix into the vial, and the concentration that results. The suggested volume reaches a clean working stock; the calculator does the arithmetic from figures you enter. These describe solution preparation for research handling — not instructions for use in humans or animals.

Suggested reconstitution Reconstitute the 10 mg vial with 2 mL bacteriostatic water → 5.0 mg/mL (5000 mcg/mL)
Concentration—
Volume / aliquot—
U-100 units—
Aliquots / vial—
Concentration = compound ÷ diluent. Volume per aliquot = target ÷ concentration. U-100 units are a volume readout (1 mL = 100 units). Figures are for research solution preparation only — not instructions for use in humans or animals.
010

Signs of a quality compound

Lyophilised cake or powder
A fine, fluffy white cake — not oily, clumped or discoloured.
Clear reconstitution
Dissolves to a clear, colourless solution with no visible particles or cloudiness.
Batch-specific COA
Independent HPLC purity and mass-spec identity for the exact lot — not a recycled generic PDF.
Intact seal & vacuum
Sealed flip-top vial under vacuum; correct fill; legible batch and storage marking.
Walk away if…
No COA, oily residue, off-colour, partial vacuum, or purity claims with no independent test behind them.
Suspiciously cheap
Pricing far below the market for a well-tested compound usually means skipped testing or underfilled vials.
Regulatory & status
Targeted, early.

KPV was removed from FDA Category 2 in April 2026 and is among the peptides under PCAC review in July 2026. It is not approved and is sold as a research material; evidence is largely preclinical.

Apr 2026
Removed from FDA Category 2
Jul 2026
PCAC 503A review · first batch
Evidence
Largely preclinical
Approval
Not approved
Research handling
Important notices
  • For research purposes only
  • Not for human consumption
  • Not FDA approved
  • Consult a qualified professional
Important

For research use only. Not for human consumption. Apex Academy is an educational reference describing findings reported in published and preclinical literature. Nothing here is medical advice, a protocol, or a recommendation to administer any compound to humans or animals. Many compounds described are investigational and are not approved by the FDA or other regulators for the prevention, treatment, or cure of any condition. Their long-term safety and pharmacokinetics remain incompletely characterized. Dose ranges, where shown, describe quantities used in cited research models - not instructions for use. Consult a qualified, licensed professional before making any health decision.