SELANK
A synthetic analog of tuftsin studied for anxiolytic and cognitive effects.
Calm without sedation.
Selank is a synthetic analog of the immune peptide tuftsin, developed in Russia and studied as an anxiolytic that, unlike benzodiazepines, does not appear to sedate or cause dependence in research settings.
At a glance
Calm, decoupled from sedation.
Selank's interest comes from a specific profile: in animal models it lowers anxiety-like behaviour without the sedation, tolerance or dependence associated with benzodiazepines.
Mechanistically it is tied to GABAergic and monoamine modulation and to raised BDNF, alongside a tuftsin-derived immune action. The human evidence is largely Russian and limited - most of the detailed work remains preclinical.
Not all claims are equal.
- Anxiolytic effects in animal models
- Non-sedating profile vs benzodiazepines
- Tuftsin-analog immune activity
- BDNF elevation and cognitive signals
- Limited human anxiety research (Russian)
- Enkephalin-stabilising activity
- Western-validated human efficacy
- Long-term safety
- Standalone nootropic claims
How it works
GABAergic tone
Modulates GABA signalling tied to anxiety.
Animal modelsBDNF
Associated with raised neurotrophic signalling.
PreclinicalEnkephalin
Slows enkephalin degradation, extending activity.
MechanisticImmune link
Retains tuftsin-like immune-modulating activity.
ResearchHow it moves through the system
Reconstitution calculator
How much diluent to mix into the vial, and the concentration that results. The suggested volume reaches a clean working stock; the calculator does the arithmetic from figures you enter. These describe solution preparation for research handling — not instructions for use in humans or animals.
Signs of a quality compound
Selank has Russian clinical history but is investigational and unapproved in most Western markets, where it is sold as a research compound.
- For research purposes only
- Not for human consumption
- Not FDA approved
- Consult a qualified professional