Compound profile · Recovery research

TB-500

Tissue research Janoshik verified
StatusResearch use only
BPC-157 - 10 mg
BPC-157 - 10 mg
Dhs. 349.00
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01

The migration peptide.

TB-500 is the research name for a synthetic form of Thymosin β4, one of the most-studied actin-regulating peptides in the literature. Its signature active region, LKKTETQ, is tied to cell migration - the process by which repair cells reach a wound.

01
Actin sequestration
Binds G-actin, regulating the cytoskeletal dynamics behind cell movement.
02
Wound models
Rodent studies report faster re-epithelialisation and contraction.
03
Often paired
Frequently studied alongside BPC-157 for complementary repair pathways.
Primary structure
Ac-Ser-Asp-Lys-Pro-Asp-Met-… (Thymosin β4, 43-aa)
Thymosin β4 · 43 amino acids · ~4963 Da
Calculate your reconstitution dosage →
03

At a glance

43
Amino acids (Tβ4)
LKKTETQ
Active fragment
—
Half-life: hours
04

One protein, many repair roles.

Thymosin β4 occurs in nearly all mammalian cells and is among the most abundant actin-binding proteins. TB-500 research focuses on its short active sequence rather than the full protein.

Reported activity spans angiogenesis, cell migration and anti-inflammatory signalling - strong, repeated findings across animal models, much like BPC-157.

05

Reading the evidence honestly

Not all claims are equal.

Tier 01
Strongest support
  • Actin binding and cell-migration regulation (well characterised)
  • Accelerated wound closure in animal models
  • Cardiac and corneal repair signals in research settings
Tier 02
Moderate / preclinical
  • Anti-inflammatory and immune-modulating effects
  • Hair-follicle and tissue-regeneration models
  • Anecdotal recovery use
Tier 03
Emerging / unverified
  • Human efficacy and dosing
  • Long-term safety profile
  • Systemic 'anti-ageing' positioning
06

How it works

Research has examined several distinct signalling pathways, summarised below.

01
Actin regulation

Sequesters G-actin, enabling the cytoskeletal remodelling behind migration.

Well characterised
02
Angiogenesis

Promotes endothelial-cell migration and vessel formation in models.

Preclinical
03
Anti-inflammatory

Down-regulates inflammatory cytokines in injury models.

Animal models
04
Tissue repair

Linked to faster re-epithelialisation across wound types.

Replicated (animal)
07

How it moves through the system

AdministrationPeakHalf-lifeCleared
Peak 50% Cleared
1 - 2 h
Onset to peak
~hours
Half-life
days
Largely cleared
Curve shape is illustrative; figures reflect pharmacokinetics reported in research — rapid local metabolism, figures from animal IV/IM data.
08

Used in the lab, not the clinic

Reference figures describe how this compound is handled and dosed in research. These are not instructions for human use.

Format & handling
Research formatLyophilised
ReconstitutionBacteriostatic water
Cold-chainRecommended
In the literature
Doses in literatureµg/kg (animal)
Storage−20 °C lyophilised
Stability (reconstituted)~weeks, refrigerated
09

Reconstitution calculator

How much diluent to mix into the vial, and the concentration that results. The suggested volume reaches a clean working stock; the calculator does the arithmetic from figures you enter. These describe solution preparation for research handling - not instructions for use in humans or animals.

Suggested reconstitution Reconstitute the 10 mg vial with 2 mL bacteriostatic water → 5.0 mg/mL (5000 mcg/mL)
Concentration—
Volume / aliquot—
U-100 units—
Aliquots / vial—
Concentration = compound ÷ diluent. Volume per aliquot = target ÷ concentration. U-100 units are a volume readout (1 mL = 100 units). Figures are for research solution preparation only — not instructions for use in humans or animals.
010

Signs of a quality compound

Lyophilised cake or powder
A fine, fluffy white cake - not oily, clumped or discoloured.
Clear reconstitution
Dissolves to a clear, colourless solution with no visible particles or cloudiness.
Batch-specific COA
Independent HPLC purity and mass-spec identity for the exact lot — not a recycled generic PDF.
Intact seal & vacuum
Sealed flip-top vial under vacuum; correct fill; legible batch and storage marking.
Walk away if…
No COA, oily residue, off-colour, partial vacuum, or purity claims with no independent test behind them.
Suspiciously cheap
Pricing far below the market for a well-tested compound usually means skipped testing or underfilled vials.
Regulatory & status
Studied widely, approved nowhere.

Despite an extensive preclinical record, TB-500 / Thymosin β4 has no general human approval and is sold as a research material. It is prohibited in competitive sport.

Status
Investigational research compound
Evidence
Extensive animal, limited human
Approval
Not FDA-approved for human use
Anti-doping
Prohibited in sport (WADA-listed)
Research handling
Important notices
  • For research purposes only
  • Not for human consumption
  • Not FDA approved
  • Consult a qualified professional
Important

For research use only. Not for human consumption. Apex Academy is an educational reference describing findings reported in published and preclinical literature. Nothing here is medical advice, a protocol, or a recommendation to administer any compound to humans or animals. Many compounds described are investigational and are not approved by the FDA or other regulators for the prevention, treatment, or cure of any condition. Their long-term safety and pharmacokinetics remain incompletely characterized. Dose ranges, where shown, describe quantities used in cited research models - not instructions for use. Consult a qualified, licensed professional before making any health decision.